Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
B2M P61769 beta-2-microglobulin Immune response 0.56 0.447 0.846
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
CALCR P30988 calcitonin receptor G-protein coupled receptor 3.1E-09 0.464 0.846
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846